Menopause is a natural process in women is characterized by decreased ovarian function resulting in decreased production of estrogen. Reduced estrogen brings a variety of problems, one of which increased the risk of heart disease.Decreased production of estrogen causes the disorder of blood fat metabolism so it will aggravate the blood lipid profile and oxidation in the body so vulnerable women suffering from coronary heart disease.body easily oxidized, thus resulting in the formation of lipid
peroxidation is characterized by increased malondialdehyde (MDA). High levels of MDA can be used as an indicator of free radicals in the body. Excess free radicals are the risk factors for degenerative diseases such as heart disease, stroke, and cancer. Lipids, especially in LDL-cholesterol (LDL-C) are known as bad cholesterol is a major target of oxidation.The occurrence of oxidation in LDL-C is one of the main factors of blood vessel blockage. To prevent this required the presence of antioxidants, one of which is the endogenous antioxidant superoxide dismutase (SOD) which is the first line of defense against oxidation processes in the body.
He said that in the last 10-12 years, research on the benefits of soy protein and isoflavones on the rise and depth, and proved that soy consumption does not only improve some aspects of health in menopausal women, but also improve cardiovascular health.known, tempeh is a traditional food which is very popular in Indonesia. The process of fermentation, so the levels of amino acids, fatty acids, and isoflavones in tempeh is much higher than soybeans.Tempe food analysis showed that the highest amino acid content in tempeh is arginine and the highest fatty acid is linoleic acid. Tempe is also rich in isoflavones and the relative levels can be maintained if the tempeh processed by steaming (not frying).Statistical test results showed that administration of 160 grams tempeh every day for four weeks can improve the lipid profile that is lower total cholesterol, C-LDL (bad) cholesterol, and triglycerides. tempeh can also increase the activity of antioxidant enzymes
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